Physician's CHOICE Probiotics 60 Billion CFU

Probiotics, often referred to as "good" or "beneficial" bacteria, are live microorganisms that are similar to those naturally found in the human gut. These tiny but mighty life forms play a crucial role in promoting a healthy digestive system and overall well-being. They are most commonly known for their presence in certain foods and supplements.

The primary function of probiotics is to maintain a healthy balance in the body's microbiota, the community of microorganisms living in our bodies. This balance is essential for several reasons. Firstly, it aids in the digestion of food, ensuring that our bodies effectively absorb the nutrients we need. Probiotics help break down complex carbohydrates, proteins, and fats, which can improve nutrient absorption and reduce symptoms of indigestion.

Another significant benefit of probiotics is their contribution to the immune system. A substantial portion of our immune system is actually located in our gut. By enhancing the gut's barrier function and producing substances that can combat harmful bacteria, probiotics play a role in boosting our immune response and reducing the risk of infections.

The top 10 Probiotics

Product name Image Rating Pros Cons Best Price More information

Physician’s CHOICE Probiotics 60 Billion CFU

Physician's CHOICE Probiotics 60 Billion CFU 4 and a half star review
  • Effective Gut Survival Design
  • High Quality and Scientifically Backed
  • Crafted to support digestive health, with a blend of diverse, high-quality probiotic strains and organic prebiotics
  • Potentially Overpowering for users with sensitive stomachs
  • no significant effect on certain digestive issues like IBS(Irritable Bowel Syndrome)
  • Some users have noted that the capsules have a noticeable and unpleasant smell
Coming Soon!

Nature’s Bounty Probiotic 10

Nature’s Bounty Probiotic 10
  • Affordable option
  • Contains ten probiotic strains
  • No refrigeration required
  • Some users may find it less effective than more specialized brands
  • Contains some synthetic ingredients
Coming Soon!

Culturelle Daily Probiotic Gummies

Culturelle Daily Probiotic Gummies
  • Contains Lactobacillus rhamnosus GG known for aiding digestion, supporting the immune system, and alleviating stomach flu symptoms
  • Trusted brand with a long history
  • The gummy format is easy and convenient to take
  • Shown potential in preventing diarrhea related to antibiotic use and may offer benefits in asthma and allergy response
  • Users may experience abdominal pain, gas, bloating
  • Specific Strain Focus limits the spectrum of benefits that some probiotics offer
  • Effectiveness can vary between individuals
Coming Soon!

Culturelle Daily Probiotic Capsules

Culturelle Daily Probiotic Capsules
  • Contains Lactobacillus rhamnosus GG, a well-researched strain
  • No refrigeration required
  • Gluten-free
  • May not contain as many diverse strains as some other products
  • May not be suitable for individuals with dairy allergies
Coming Soon!

Garden of Life Dr Formulated Probiotics

Garden of Life Dr Formulated Probiotics
  • Contains a Wide range of strains
  • Certified organic and non-GMO
  • Shelf-stable
  • Some users may find it expensive
  • May need to take multiple capsules per serving
Coming Soon!

Align Probiotics for Women and Men

Align Probiotics for Women and Men
  • Contains Bifidobacterium 35624™, a specific strain for digestive health
  • No refrigeration needed
  • Recommended by a number of gastroenterologists
  • Limited strain diversity
  • May not be suitable for those with lactose intolerance
Coming Soon!

Renew Life Ultimate Flora

Renew Life Ultimate Flora
  • Offers a variety of formulas for different needs (e.g., women's health, colon care)
  • High potency
  • Some users report a complete overhaul of their stomach issues. No more burps, bloating, or being scared to eat.
  • May require refrigeration
  • Can be pricey compared to other options
Coming Soon!

NOW Supplements Probiotic-10

NOW Supplements Probiotic-10
  • Contains ten probiotic strains
  • Affordable option
  • Suitable for vegetarians and vegans
  • May require refrigeration for long-term stability
  • Some users may experience gastrointestinal discomfort
Coming Soon!

Hyperbiotics Pro 15 Vegan Probiotic

Hyperbiotics Pro 15 Vegan Probiotic
  • Contains 15 probiotic strains
  • Delayed-release capsules for better absorption
  • No refrigeration needed
  • Some users may experience initial bloating or gas
  • May not be suitable for those with severe lactose intolerance
Coming Soon!

SmartyPants Adult Probiotic Immunity Gummies

SmartyPants Adult Probiotic Immunity Gummies
  • Tasty gummies that are easy to take
  • No refrigeration required
  • Suitable for children
  • Lower probiotic count compared to some capsules
  • Contains added sugar
Coming Soon!

Additional Reading

Probiotics are also valuable for gut health, particularly in addressing gastrointestinal issues. They can be beneficial in managing conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and infectious diarrhea. By promoting a healthy balance of gut bacteria, probiotics can alleviate symptoms like bloating, gas, and abdominal pain.

Mental health benefits are an emerging area of interest in probiotic research. The gut-brain axis, a communication network linking the gut and brain, suggests that gut health can influence mental health. Some studies have shown that probiotics may have a positive impact on mood and could potentially assist in managing conditions like depression and anxiety.

Probiotics can be found in various foods, especially fermented foods like yogurt, kefir, sauerkraut, tempeh, and kimchi. These foods naturally contain beneficial bacteria, making them excellent dietary sources of probiotics. For those who do not consume these foods regularly, probiotic supplements are available. These supplements come in various forms, such as capsules, tablets, and powders, and contain specific strains of bacteria intended to provide health benefits.

While probiotics are generally considered safe for most people, it's always advisable to consult a healthcare professional before starting any new supplement regimen, especially for individuals with underlying health conditions or those taking other medications.

The History of Probiotics

Probiotics, often hailed as beneficial bacteria, have a history that is as fascinating as their impact on human health. The concept of probiotics can be traced back to the early 20th century, stemming from the work of Nobel laureate Elie Metchnikoff. Metchnikoff, a Russian scientist working at the Pasteur Institute in Paris, was the first to suggest the possibility of modifying the gut flora and replacing harmful microbes with useful ones. This revolutionary idea emerged from his observation that certain rural populations in Bulgaria, known for their unusually long lifespans, consumed large amounts of fermented dairy products.

This initial spark of interest led to the identification of what we now call probiotics—live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. The term "probiotic," combining "pro" and "bios," meaning "for life," was coined much later in the mid-20th century. This was a period marked by scientific advancements in microbiology, which allowed for a deeper understanding of these beneficial microorganisms.

The most common types of microorganisms used as probiotics are Lactobacillus and Bifidobacterium. They are predominantly found in fermented foods such as yogurt, kefir, sauerkraut, and kimchi. However, with the rise of commercial interest and scientific research in the late 20th century, probiotics have also been incorporated into dietary supplements and even specific food products designed to enhance gut health.

The growing body of scientific research over the years has indicated that probiotics can be beneficial in treating and preventing a variety of health issues. These range from digestive disorders like irritable bowel syndrome and antibiotic-associated diarrhea to potentially influencing mental health through the gut-brain axis. The latter is an exciting area of research, often referred to as the "psychobiotic" potential of probiotics.

Today, the use of probiotics has become increasingly mainstream, bolstered by a greater public awareness of gut health's impact on overall well-being. However, it's important to note that the field of probiotics is complex and evolving. The effects of probiotics can vary based on the specific strain, dose, and individual to whom they are administered. This has led to a more nuanced understanding of probiotics, with ongoing research seeking to tailor probiotic treatments to individual needs and health conditions.

Ingredients of Probiotics

Probiotics are composed of specific strains of live microorganisms that confer health benefits when consumed in adequate amounts. The primary ingredients in probiotic supplements or foods are these beneficial bacteria or yeasts. Here are some of the key components:
  • Lactic Acid Bacteria: This is the most common type of bacteria used in probiotics. They include:
    • Lactobacillus species: Such as L. acidophilus, L. rhamnosus, L. casei, and L. bulgaricus. These are often found in yogurt and other fermented dairy products.
    • Bifidobacteria species: Including B. bifidum, B. longum, and B. lactis, commonly found in dairy products.
  • Yeast: Some probiotics contain yeast, particularly Saccharomyces boulardii, which is beneficial in treating and preventing certain gastrointestinal disorders.
  • Streptococcus species: For example, Streptococcus thermophilus, which is also used in the fermentation of dairy products like yogurt and cheese.
In addition to these live microorganisms, probiotic supplements might contain other ingredients, such as:
  • Prebiotics: These are non-digestible fibers that help nourish and promote the growth of beneficial bacteria in the gut. Examples include inulin and fructooligosaccharides (FOS).
  • Fillers and binders: Substances like cellulose or silicon dioxide might be used in probiotic capsules to help stabilize the product.
  • Enteric coatings: Some probiotic capsules are coated with a material that prevents the capsule from dissolving in the stomach, ensuring the bacteria reach the intestines where they are most effective.

Who should use Probiotics

Probiotics are beneficial for a wide range of individuals, particularly those seeking to improve or maintain their gut health. However, certain groups of people may find them especially useful:
  • Individuals with Digestive Disorders: Probiotics can be beneficial for those suffering from conditions such as irritable bowel syndrome (IBS), inflammatory bowel diseases (like Crohn's disease and ulcerative colitis), and chronic constipation. They help in balancing the gut microbiota, which can alleviate symptoms.
  • People Taking Antibiotics: Antibiotics can disrupt the natural balance of gut bacteria. Probiotics can help replenish beneficial bacteria, reducing the risk of antibiotic-associated diarrhea.
  • Those with a Weakened Immune System: Since a significant part of the immune system is located in the gut, probiotics can help strengthen immune responses, benefiting individuals with weakened immune systems, either due to illnesses or as a result of taking certain medications.
  • Individuals Suffering from Allergies and Eczema: Some evidence suggests that probiotics can help in managing allergies and eczema, particularly in children and infants.
  • People Seeking to Improve Mental Health: Emerging research indicates that gut health can impact mental health. Probiotics, therefore, might benefit those dealing with stress, anxiety, or depression.
  • Those Managing Metabolic Health Conditions: Probiotics may have a role in managing conditions like obesity, type 2 diabetes, and metabolic syndrome by improving gut health and reducing inflammation.

Who should NOT use Probiotics

While probiotics are generally safe for most people, there are specific situations and conditions where their use might be inappropriate or require careful consideration:
  • People with Compromised Immune Systems: Individuals with weakened immune systems, such as those undergoing chemotherapy, living with HIV/AIDS, or taking immunosuppressive drugs, should be cautious. Probiotics can potentially pose a risk of infections in such cases.
  • Patients with Critical Illnesses: Those who are critically ill, especially those in intensive care units or with severe acute pancreatitis, should avoid probiotics. In rare cases, probiotics could lead to infections or other complications in critically ill patients.
  • Post-Surgical Patients: Individuals who have recently undergone surgery should consult their doctors before taking probiotics. There's a potential risk of bacterial or fungal infections via translocation – the passage of bacteria from the gut to other parts of the body.
  • People with Certain Pre-existing Gut Conditions: Those with conditions like Small Intestinal Bacterial Overgrowth (SIBO) or those with a history of gut permeability (leaky gut) should approach probiotics with caution, as they might exacerbate symptoms.
  • Infants and Young Children: The safety and efficacy of probiotics in very young children, especially premature infants, have not been thoroughly established. It's essential to consult a pediatrician before administering probiotics to infants and young children.
  • Allergic or Sensitive Individuals: People with allergies to certain ingredients in probiotic supplements, such as lactose or soy, or those who have had allergic reactions to probiotic-rich foods, should avoid probiotics or choose hypoallergenic variants.

Pros and Cons of Probiotics


  • Gut Health Improvement: Probiotics help balance the gut microbiome, which is crucial for digestion, nutrient absorption, and overall gastrointestinal health. They can alleviate symptoms of irritable bowel syndrome (IBS), inflammatory bowel diseases, and antibiotic-associated diarrhea.
  • Boosting Immune Function: A significant portion of the immune system is located in the gut. Probiotics can strengthen the immune response, potentially reducing the frequency of colds, flu, and other infections.
  • Mental Health Benefits: Emerging research suggests a link between gut health and mental health. Probiotics may play a role in managing mood, stress, anxiety, and depression through the gut-brain axis.
  • Managing Allergies and Skin Conditions: Probiotics have shown promise in managing allergic reactions and skin conditions like eczema, particularly in children
  • Support in Metabolic Health: They may assist in managing obesity, type 2 diabetes, and metabolic syndrome by improving gut health, reducing inflammation, and potentially influencing metabolism.
  • Support During and After Antibiotic Use: Probiotics can replenish beneficial gut bacteria disrupted by antibiotic treatment, reducing the risk of antibiotic-associated diarrhea and restoring gut flora balance.
  • Beneficial for Certain Chronic Diseases: Research indicates potential benefits in managing chronic diseases like heart disease, and certain types of cancers, by reducing inflammation and promoting a healthy gut environment.
  • Child Development: Early evidence suggests probiotics can be beneficial in early life, supporting the development of a healthy immune system and potentially reducing the risk of certain childhood diseases.


  • Potential for Infections: In immunocompromised individuals, probiotics can sometimes cause infections by introducing new bacterial strains into a weakened system.
  • Side Effects: Some people may experience mild side effects like bloating, gas, or discomfort, especially when starting probiotics or trying new strains.
  • Limited Regulation: Dietary supplements, including probiotics, are not as tightly regulated as pharmaceuticals. This can lead to variability in quality and potency between different products.
  • Ineffectiveness for Some: Probiotics do not work uniformly for everyone. Some individuals may not experience any benefits, depending on their unique gut flora and health conditions.
  • Interaction with Medications: Probiotics can interact with certain medications, altering their effectiveness. It's essential to consult with healthcare providers about potential interactions.
  • Unclear Optimal Strains and Dosages: There is still ongoing research to determine the most effective strains and dosages for specific conditions, making it challenging to choose the right probiotic.
  • Cost and Accessibility: High-quality probiotics can be expensive, and not everyone may have access to them or be able to afford them consistently.
  • Risk for Certain Populations: Pregnant women, infants, elderly individuals, and those with certain pre-existing conditions should use probiotics cautiously and under medical supervision.

Studies regarding the benefits of Probiotics

Title: Unraveling the Puzzle: Health Benefits of Probiotics—A Comprehensive Review
Summary: This study explores how probiotics support gut microbiota health, potentially preventing or delaying gastrointestinal disorders, obesity, type 2 diabetes, autism, osteoporosis, and some immunological illnesses. It highlights the varied beneficial properties of probiotics depending on the microbial strain used​​.

Title: Therapeutic, Prophylactic, and Functional Use of Probiotics: A Current Perspective
Summary: This research delves into the extensive application of probiotics in foods and supplements, discussing nearly 2,000 clinical studies on their health benefits. It highlights the challenges in delivering probiotics effectively and their varied actions in enhancing gut health and immune function.

Title: The Anti-Inflammatory and Curative Exponent of Probiotics: A Comprehensive and Authentic Ingredient for the Sustained Functioning of Major Human Organs
Summary: This review focuses on the role of probiotics in preventing ailments in major organs, particularly their immediate activation of anti-inflammatory mechanisms and the production of cytokines​​.

Title: Probiotics: A Comprehensive Review of Their Classification, Mode of Action, and Role in Human Nutrition
Summary: This study examines the effectiveness of probiotics in preventing pathogenic colonization and their potential role in cancer protection and cardiovascular health​.

Title: Nutritional and Health Potential of Probiotics: A Review
Summary: This review discusses the potential uses of probiotics in preventing gastrointestinal problems, obesity, type 2 diabetes, and some immunological disorders. It also explores their role in improving oral, nutritional, and intestinal health​​.

Frequently Asked Questions about Probiotics

What are Probiotics and How Do They Work?

Probiotics are live microorganisms, primarily bacteria and yeast, that are beneficial to human health, particularly the digestive system. They are often referred to as “good” or “friendly” bacteria because they help keep the gut healthy. Common probiotic strains include Lactobacillus, Bifidobacterium, and Saccharomyces boulardii.

How Probiotics Work:

  1. Balancing the Gut Microbiota:
    • Gut Microbiota: The human gut is home to trillions of microorganisms, including bacteria, viruses, fungi, and other microbes, collectively known as the gut microbiota. A balanced gut microbiota is essential for overall health.
    • Restoring Balance: Probiotics help restore and maintain a healthy balance of gut bacteria. They compete with harmful bacteria for nutrients and attachment sites in the gut lining, thereby inhibiting the growth of pathogenic microbes.
  2. Enhancing the Gut Barrier:
    • Intestinal Barrier: The gut lining acts as a barrier to prevent harmful substances from entering the bloodstream. A healthy gut barrier is crucial for preventing infections and inflammation.
    • Strengthening the Barrier: Probiotics enhance the integrity of the gut barrier by promoting the production of mucus and strengthening tight junctions between cells in the gut lining. This helps prevent leaky gut syndrome and protects against harmful pathogens.
  3. Modulating the Immune System:
    • Immune Function: A significant portion of the immune system is located in the gut. Probiotics interact with immune cells and influence immune responses.
    • Immune Modulation: Probiotics can enhance the production of antibodies, stimulate the activity of macrophages (cells that engulf and destroy pathogens), and modulate the balance of pro-inflammatory and anti-inflammatory cytokines (signaling molecules). This helps in boosting overall immunity and reducing inflammation.
  4. Producing Beneficial Substances:
    • Short-Chain Fatty Acids (SCFAs): Probiotics produce SCFAs like acetate, propionate, and butyrate by fermenting dietary fibers. SCFAs provide energy to gut cells, enhance gut barrier function, and have anti-inflammatory effects.
    • Vitamins and Enzymes: Some probiotics produce vitamins (e.g., vitamin K and certain B vitamins) and enzymes that aid in digestion and nutrient absorption.
  5. Competing with Pathogens:
    • Colonization Resistance: Probiotics compete with harmful bacteria for nutrients and binding sites on the gut lining. This process, known as colonization resistance, helps prevent infections by pathogenic microbes.
    • Producing Antimicrobial Substances: Some probiotics produce antimicrobial compounds (bacteriocins) that inhibit the growth of harmful bacteria.

Benefits of Probiotics:

  1. Digestive Health:
    • Relieve symptoms of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).
    • Prevent and treat diarrhea, including antibiotic-associated and traveler’s diarrhea.
    • Alleviate constipation and bloating.
  2. Immune Support:
    • Enhance immune response and reduce the frequency and duration of infections.
    • Modulate the immune system to reduce inflammation and prevent allergies.
  3. Mental Health:
    • Influence the gut-brain axis to potentially improve mood, reduce anxiety, and alleviate symptoms of depression.
  4. Heart Health:
    • Help lower blood pressure and cholesterol levels, supporting cardiovascular health.
  5. Skin Health:
    • Improve conditions like eczema and acne through their anti-inflammatory and immune-modulating effects.
  6. Weight Management:
    • Aid in weight loss and weight management by influencing metabolism and fat storage.

Sources of Probiotics:

  1. Fermented Foods:
    • Yogurt: Contains live cultures like Lactobacillus and Bifidobacterium.
    • Kefir: A fermented milk drink with diverse probiotic strains.
    • Sauerkraut and Kimchi: Fermented vegetables rich in beneficial bacteria.
    • Miso and Tempeh: Fermented soybean products.
    • Kombucha: A fermented tea beverage.
  2. Probiotic Supplements:
    • Available in various forms, including capsules, tablets, powders, and liquids. They provide concentrated doses of specific probiotic strains and are convenient for individuals who may not consume enough fermented foods.

What are the health benefits of taking probiotics?

Probiotics offer various health benefits, including:

  • Improving Digestive Health: Alleviating symptoms of irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diarrhea.
  • Boosting Immune Function: Enhancing the body’s natural defenses against infections.
  • Preventing and Treating Diarrhea: Especially antibiotic-associated diarrhea and traveler’s diarrhea.
  • Supporting Mental Health: Potential benefits for anxiety, depression, and cognitive function through the gut-brain axis.
  • Promoting Heart Health: Helping to lower blood pressure and cholesterol levels.
  • Managing Allergies and Eczema: Reducing symptoms of allergic reactions and skin conditions.
  • Enhancing Nutrient Absorption: Improving the digestion and absorption of nutrients like vitamins and minerals.

Are probiotics safe to use, and what are the potential side effects?

  • Probiotics are generally considered safe for most people. However, some individuals may experience side effects, including:
    • Digestive Symptoms: Such as gas, bloating, or diarrhea, typically temporary as the body adjusts.
    • Infections: Rare but possible, especially in immunocompromised individuals.
    • Allergic Reactions: Rare but can occur in response to certain probiotic strains or ingredients.

    It is essential to choose high-quality probiotics from reputable brands and consult with a healthcare provider, especially if you have underlying health conditions.

How should probiotics be taken, and what is the recommended dosage?

Probiotics should be taken according to the instructions on the product label or as advised by a healthcare provider. General guidelines include:

  • Dosage: Typically measured in colony-forming units (CFUs), with common doses ranging from 1 billion to 100 billion CFUs per day.
  • Timing: Can be taken with or without food, but some evidence suggests taking probiotics with a meal can enhance their survival through the digestive tract.
  • Consistency: Regular daily intake is important for maintaining the benefits.

Can probiotics interact with other medications or supplements?

Probiotics are generally safe to take with most medications and supplements. However, potential interactions include:

  • Antibiotics: Probiotics can help restore gut flora disrupted by antibiotics, but they should be taken a few hours apart to avoid reducing the effectiveness of either.
  • Immunosuppressants: Individuals on immunosuppressive therapy should consult with their healthcare provider, as probiotics can stimulate the immune system.

Are there different types of probiotics, and do they have specific benefits?

Yes, different probiotic strains offer specific benefits:

  • Lactobacillus: Commonly used for digestive health, lactose intolerance, and preventing diarrhea.
  • Bifidobacterium: Often used for IBS, IBD, and general gut health.
  • Saccharomyces boulardii: Effective for preventing and treating diarrhea, including antibiotic-associated and traveler’s diarrhea.
  • Streptococcus thermophilus: Used in yogurt fermentation, supporting digestive health and lactose digestion.

The choice of probiotic strain should match your specific health goals and needs.

Can probiotics help with weight loss?

Some studies suggest that certain probiotic strains may aid in weight loss and management by:

  • Regulating Appetite: Influencing hormones related to hunger and satiety.
  • Reducing Fat Storage: Altering the gut microbiota composition to reduce fat absorption.
  • Enhancing Metabolism: Improving metabolic function and reducing inflammation.

However, more research is needed to confirm these effects, and probiotics should be part of a comprehensive weight management plan including diet and exercise.

Can children take probiotics, and are there specific benefits for them?

Yes, children can take probiotics, and they may benefit from:

  • Improved Digestive Health: Reducing symptoms of colic, constipation, and diarrhea.
  • Enhanced Immune Function: Reducing the frequency and severity of infections.
  • Allergy Management: Potentially reducing the risk and severity of eczema and allergies.

It is important to choose age-appropriate probiotic formulations and consult with a pediatrician before starting probiotics for children.

How do I choose a high-quality probiotic supplement?

When selecting a probiotic supplement, consider the following factors:

  • Strain Specificity: Look for clinically studied strains that match your health needs.
  • CFU Count: Choose a product with an adequate number of CFUs.
  • Storage Requirements: Check if the probiotic needs refrigeration or is shelf-stable.
  • Expiration Date: Ensure the product is within its shelf life for maximum potency.
  • Third-Party Testing: Look for products tested for quality, purity, and potency.
  • Brand Reputation: Choose reputable brands with positive reviews and transparent practices.

Can probiotics be obtained from food, and what are the best sources?

Yes, probiotics can be obtained from fermented foods, including:

  • Yogurt: Contains live cultures like Lactobacillus and Bifidobacterium.
  • Kefir: A fermented milk drink rich in diverse probiotic strains.
  • Sauerkraut: Fermented cabbage providing Lactobacillus.
  • Kimchi: A spicy Korean fermented vegetable dish.
  • Miso: A Japanese fermented soybean paste.
  • Tempeh: Fermented soybeans forming a dense cake.
  • Kombucha: A fermented tea drink.

Incorporating these foods into your diet can provide natural sources of probiotics, supporting gut health and overall well-being.