XTEND Original BCAA Powder

BCAA supplements, or branched-chain amino acid supplements, are a group of three essential amino acids: leucine, isoleucine, and valine. Being termed "essential" means that our bodies cannot produce these amino acids on their own, and we must obtain them from our diets or supplements. These amino acids are termed "branched-chain" due to their chemical structure, which features a side chain that branches off to one side.

BCAAs are unique among amino acids because they are primarily metabolized in skeletal muscle, rather than the liver. Because of this, they play a crucial role in muscle metabolism and are often taken to support muscle growth and enhance exercise performance. They can also serve as a source of energy during exercise, especially when muscle glycogen stores are low.

The top 10 BCAA Supplements

Product name Image Rating Pros Cons Best Price More information

XTEND Original BCAA Powder

XTEND Original BCAA Powder
  • Contains electrolytes for added hydration benefits
  • Comes in a variety of delicious flavors
  • Often praised for its mixability in water
  • Contains artificial sweeteners which some users avoid
  • Some flavors might taste too strong or artificial
  • Might be pricier than other brands
Coming Soon!

MusclePharm Essentials BCAA

MusclePharm Essentials BCAA
  • Offers a patented 3:1:2 ratio for a unique approach to BCAAs
  • No artificial dyes or colors
  • Suitable for athletes as it's Informed-Choice certified
  • Some users might not prefer the altered ratio
  • The flavor might be mild for some
  • Might not dissolve as easily as other brands
Coming Soon!

Evlution EVL BCAAs Amino Acids Powder

Evlution EVL BCAAs Amino Acids Powder
  • Provides 5,000 mg of BCAAs per serving
  • Comes in both capsule and powder form
  • Contains no carbohydrates or sugars
  • Some might find flavors too sweet
  • Might not have as many flavor options as competitors
  • Some users reported digestive discomfort
Coming Soon!

Optimum Nutrition Superior Amino

Optimum Nutrition Superior Amino Capsules 4 and a half star review
  • Widely recognized brand with a reputation for quality
  • Offers a 2:1:1 ratio of leucine to isoleucine to valine
  • Convenient capsule form for easy consumption
  • Capsules might be large and difficult for some to swallow
  • May contain additional fillers or binders
  • Some users might prefer a flavored powder form
Coming Soon!


  • Pure powder with no added fillers or flavors
  • Suitable for those who want to avoid additives
  • Offers flexibility in dosing
  • Unflavored powder might taste bitter
  • Requires precise measurement
  • Some users might miss the added benefits of electrolytes or other ingredients
Coming Soon!

BPI Sports Best BCAA

BPI Sports Best BCAA supplements
  • Contains a CLA matrix for added fat-burning benefits
  • Offers a range of unique flavors
  • Easy to mix in beverages
  • Contains artificial colors and sweeteners
  • Some users might experience an aftertaste
  • The consistency might feel slightly thick or viscous for some
Coming Soon!

Dymatize All9 Amino

Dymatize All9 Amino
  • Offers BCAAs in a time-release formula
  • Contains added vitamin B6 for enhanced absorption
  • Convenient tablet form
  • Contains added fillers
  • Tablets might be larger than average capsules
  • Some users might require multiple tablets for a full dose
Coming Soon!

Myprotein BCAA 2-1-1

Myprotein BCAA 2-1-1
  • Known for high purity and quality
  • Comes in both flavored and unflavored varieties
  • Often more affordable than competitors
  • The unflavored version might be particularly bitter
  • Some flavors might not taste natural
  • Mixability might be an issue for some
Coming Soon!

Cellucor Alpha Amino EAA & BCAA Powder

Cellucor Alpha Amino EAA & BCAA Powder
  • Contains a hydration blend with electrolytes
  • Offers a variety of flavors
  • Contains proprietary blends, making it hard to know exact amounts of each ingredient
  • Some users find it too sweet or artificially flavored
  • Might be pricier than other options
  • A bit on the pricier side for natural products
Coming Soon!

AminoOne BCAA Powder Supplement

AminoOne BCAA Powder Supplement
  • No artificial flavors or colors
  • Contains additional nutrients like glutamine and citrulline
  • Vegan-friendly
  • Might not offer as many flavor choices
  • Some users find the taste too mild
  • Might not mix as well in cold water
Coming Soon!

Additional Reading

One of the primary reasons athletes and fitness enthusiasts take BCAA supplements is for muscle recovery and reduction of muscle soreness. After intense physical activity, muscles can become sore due to tiny tears in the muscle fibers. BCAAs can help accelerate the repair of these microtears, thus reducing the duration and intensity of muscle soreness.

Leucine, one of the three BCAAs, is particularly notable for its role in stimulating muscle protein synthesis. This process is essential for muscle growth and repair. It's believed that leucine activates a pathway in the body that stimulates muscle protein synthesis, which is why it's often highlighted in discussions about muscle-building and recovery.

Apart from muscle growth and recovery, BCAAs are also believed to have benefits in reducing exercise fatigue. During prolonged exercise, BCAAs can be used by the muscles as an energy source. Additionally, BCAAs might benefit brain function by promoting the synthesis of neurotransmitters and can possibly reduce symptoms of depression and improve cognitive function.

Furthermore, BCAA supplements are often recommended for individuals on low-protein diets or those who are not consuming sufficient amounts of BCAAs from food sources. They can be especially beneficial for vegetarians or vegans who might not get enough BCAAs from plant-based sources.

While BCAA supplements offer numerous benefits, it's also essential to approach their consumption with a balanced view. It's always best to obtain nutrients, including amino acids, from whole food sources when possible. Whole foods offer a complete nutritional profile, including other beneficial compounds that might not be present in isolated supplements. Additionally, while BCAAs can support muscle growth, they are only three of the nine essential amino acids, and the body requires all of them for optimal muscle protein synthesis.

The History of BCAA Supplements

The history of Branched-Chain Amino Acid (BCAA) supplements is deeply intertwined with the understanding and study of amino acids in human physiology. BCAAs, which include leucine, isoleucine, and valine, are essential amino acids, meaning they must be obtained through diet or supplementation as the body cannot produce them.

The use of BCAA supplements in the fitness and bodybuilding communities gained prominence due to their role in muscle protein synthesis and energy production during exercise. They were found to be unique among essential amino acids, as they are metabolized primarily in skeletal muscle, unlike other amino acids that are metabolized in the liver.

One of the critical turning points in the history of BCAA supplements was the realization of their potential benefits in exercise and muscle recovery. Research indicated that BCAAs could reduce muscle soreness after intense physical activities. This is attributed to their role in decreasing muscle damage, which in turn lessens the length and severity of Delayed Onset Muscle Soreness (DOMS). BCAAs also help restore glycogen and nutrients faster in the body, reducing DOMS further.

However, the journey of BCAA supplements has not been without its challenges and criticisms. Concerns have been raised about their impact on other aspects of health, such as B-vitamin depletion and potential disturbances in sleep patterns due to altered serotonin levels. High doses of BCAAs can deplete important B-vitamins in the body, which play a crucial role in amino acid metabolism and various biological processes. Moreover, BCAAs may reduce serotonin levels, affecting mood and potentially causing sleep disturbances.

Despite these concerns, BCAA supplements have remained popular in the fitness industry, particularly among those looking to enhance muscle growth, improve workout performance, and support recovery processes. The evolution of BCAA supplements reflects a broader narrative of how dietary supplements have become integral to modern fitness and health regimes.

Ingredients of BCAA Supplements

BCAA supplements primarily contain three essential amino acids: leucine, isoleucine, and valine. These are the key active ingredients in most BCAA formulations. The ratio of these amino acids can vary, with a common ratio being 2:1:1 (leucine:isoleucine:valine), though other ratios like 4:1:1 or 3:1:2 are also used.

In addition to the main amino acids, BCAA supplements may contain several other ingredients, depending on the specific product:
  • Flavorings and Sweeteners To improve taste, BCAA supplements often include natural or artificial flavorings and sweeteners. Common sweeteners include sucralose, stevia, or aspartame.
  • Colorings Some BCAA supplements may have artificial or natural colorings added to enhance their visual appeal.
  • Fillers and Binders These are used to give the product bulk and may include ingredients like cellulose, silica, or magnesium stearate.
  • Electrolytes Some BCAA formulations include electrolytes like sodium, potassium, or magnesium to support hydration, especially in products designed for use during or after exercise.
  • Other Amino Acids or Supplements Certain BCAA products might include additional amino acids like glutamine or beta-alanine, or other supplements like caffeine or creatine, to enhance their performance-enhancing effects.
  • Vitamins and Minerals Occasionally, BCAA supplements are fortified with vitamins and minerals to support overall health and workout recovery.
It's important to read the label of any BCAA supplement for a complete list of ingredients, as formulations can vary widely between products. Additionally, users should be aware of any potential allergens or substances that might conflict with dietary restrictions or medical conditions.

Who should take BCAA Supplements

  • Athletes and Bodybuilders BCAAs are popular among athletes and bodybuilders for their role in muscle protein synthesis, which is crucial for muscle growth and repair. These supplements can help enhance exercise performance and reduce muscle soreness post-exercise.
  • Individuals on a Low-Protein Diet Those who may not get sufficient essential amino acids from their diet, such as people following a vegetarian or vegan diet, might benefit from BCAA supplements to ensure they're meeting their amino acid needs.
  • People Engaged in Intense Exercise Routines Individuals involved in rigorous training or endurance sports may find BCAAs helpful in reducing muscle damage and fatigue, thus improving recovery time.
  • Weight Management BCAA supplements can be a low-calorie way to support muscle maintenance, which can be beneficial for those on a weight loss or weight management program.
  • Individuals in Muscle Recovery or Rehabilitation For people recovering from injuries or surgery, particularly where muscle loss is a concern, BCAAs can aid in muscle synthesis and preservation.

What BCAA Supplements are NOT intended for

While BCAA (Branched-Chain Amino Acid) supplements can be beneficial for many, certain individuals should exercise caution or avoid them:
  • People with ALS (Lou Gehrig’s Disease) There is some evidence to suggest that BCAAs may exacerbate symptoms of ALS, so individuals with this condition are generally advised to avoid these supplements.
  • Individuals with Branched-Chain Ketoaciduria (Maple Syrup Urine Disease) People with this rare genetic disorder have difficulty breaking down BCAAs, and thus should not take BCAA supplements.
  • Pregnant or Breastfeeding Women Due to a lack of extensive research on the effects of BCAAs on fetal development and infants, it is generally recommended that pregnant or breastfeeding women avoid these supplements.
  • Individuals with Certain Kidney or Liver Diseases As BCAAs are metabolized in the muscles and can put additional strain on the kidneys and liver, those with pre-existing conditions affecting these organs should consult a healthcare provider before using BCAA supplements.
  • People Scheduled for Surgery BCAAs might affect blood sugar levels and could interfere with blood sugar control during and after surgery. It's usually recommended to stop using BCAA supplements at least 2 weeks before a scheduled surgery.

Pros and Cons table of BCAA Supplements


  • BCAAs, particularly leucine, stimulate muscle protein synthesis, crucial for muscle growth and repair.
  • BCAAs can reduce the sensation of fatigue during exercise by influencing brain neurotransmitter levels.
  • They can reduce muscle damage, thereby lessening the severity and duration of delayed-onset muscle soreness (DOMS).
  • BCAAs have low calories and can be a beneficial addition to a calorie-deficit diet or intermittent fasting.
  • Beneficial for athletes and bodybuilders engaged in intense training sessions for energy and recovery.
  • BCAAs can be helpful for people who need to manage their blood sugar levels, such as those on ketogenic diets.
  • They help in faster recovery post-workout by aiding in muscle repair and replenishment of glycogen stores.
  • Available in various forms like powders, capsules, and ready-to-drink beverages, making them easy to incorporate into different diets.


  • High levels of BCAAs can deplete B-vitamins, which are important for amino acid metabolism and various biological functions.
  • BCAAs can interfere with the brain's serotonin synthesis, potentially affecting mood and causing sleep disturbances.
  • BCAAs do not provide all essential amino acids or other nutrients found in complete protein sources like meat or dairy.
  • Excessive intake of BCAAs, particularly leucine, may affect insulin activity and glucose uptake, impacting blood sugar levels.
  • Overuse can lead to an imbalance in amino acid levels and potentially interfere with normal protein metabolism.
  • Individuals with certain medical conditions, like ALS or branched-chain ketoaciduria, should avoid BCAAs.
  • Some BCAA supplements may contain additives and fillers that could be unnecessary or harmful.
  • BCAA supplements can be more expensive than other protein sources that offer a broader range of amino acids and nutrients.

Studies regarding BCAA Supplements

    1. Title: Effect of Branched-Chain Amino Acid Supplementation on Recovery Following Acute Eccentric Exercise
    • Summary: This study suggests BCAAs might slightly reduce muscle soreness after exercise but found no significant impact on muscle force recovery.
    1. Title: Influence of Branched-Chain Amino Acid Supplementation on Serum Amino Acid Concentrations and Muscle Protein Turnover in Healthy Adults at Rest and After Exercise
    • Summary: This study indicates that BCAA supplementation may increase muscle protein synthesis, potentially aiding recovery.
    1. Title: Branched-Chain Amino Acid Supplementation during Aerobic Exercise Training
    • Summary: This review finds limited evidence for BCAAs enhancing performance or recovery in endurance athletes.
    1. Title: The Role of Leucine in Protein Metabolism and Muscle Growth
    • Summary: This review highlights leucine's role in stimulating muscle protein synthesis, but emphasizes the importance of adequate overall protein intake.
    1. Title: Branched-Chain Amino Acid Supplementation and Exercise Performance
    • Summary: This review concludes that BCAA supplementation likely offers no significant benefit for muscle growth or strength gains in resistance-trained individuals consuming adequate protein.
    1. Title: Cognitive Function and BCAA Supplementation
    • Summary: This review explores the potential link between BCAA deficiency and cognitive decline, but evidence for BCAA supplementation improving cognitive function in healthy individuals is limited.
    1. Title: B-Vitamins and the Brain: Mechanisms, Dose and Efficacy
    • Summary: While not specifically focusing on BCAA supplementation, this review highlights the potential role of B vitamins (including some BCAAs) in brain health, suggesting further research is needed.
    1. Title: Effect of Folic Acid Supplementation on Cognitive Function in Older Adults
    • Summary: This study investigates the impact of folic acid (a B vitamin) on cognitive function, suggesting potential benefits but highlighting the need for more research.
    1. Title: Vitamin B12, Folic Acid, and Homocysteine in Alzheimer Disease
    • Summary: This research explores the potential role of B vitamins in the development and progression of Alzheimer's disease, but the specific effects of BCAA supplementation require further investigation.
    1. Title: The Role of B Vitamins in Pregnancy
    • Summary: This article discusses the importance of B vitamins during pregnancy for both mother and baby, emphasizing the need for adequate dietary intake rather than solely relying on supplementation.

Frequently Asked Questions about BCAA Supplements

What are BCAA supplements, and what do they contain?

BCAA supplements contain three essential amino acids: leucine, isoleucine, and valine. These amino acids are called “branched-chain” due to their chemical structure. They are essential because the body cannot produce them on its own; they must be obtained through diet or supplements. BCAAs play a crucial role in muscle protein synthesis, energy production during exercise, and reducing muscle breakdown.

What are the benefits of taking BCAA supplements?

The benefits of taking BCAA supplements include:

  • Enhanced Muscle Protein Synthesis: BCAAs, particularly leucine, stimulate muscle protein synthesis, aiding in muscle growth and recovery.
  • Reduced Muscle Soreness: BCAAs can help decrease muscle damage and soreness following intense exercise.
  • Improved Exercise Performance: BCAAs provide an additional energy source during prolonged exercise, potentially improving endurance.
  • Reduced Fatigue: BCAAs may help reduce exercise-induced fatigue by preventing the increase of serotonin in the brain.
  • Preservation of Lean Muscle Mass: During periods of calorie restriction or intense training, BCAAs help prevent muscle breakdown.

How do BCAA supplements work in the body?

BCAA supplements work by directly entering the bloodstream and being taken up by the muscles. Leucine, in particular, activates a key pathway in the body that stimulates muscle protein synthesis. During exercise, BCAAs are used as an energy source, sparing muscle glycogen and preventing muscle breakdown. They also compete with tryptophan for entry into the brain, reducing the production of serotonin and delaying fatigue.

When is the best time to take BCAA supplements?

The best time to take BCAA supplements can vary based on individual goals and training schedules:

  • Pre-Workout: Taking BCAAs before exercise can help reduce muscle fatigue and provide an energy boost.
  • Intra-Workout: Consuming BCAAs during exercise can help maintain energy levels and prevent muscle breakdown.
  • Post-Workout: Taking BCAAs after exercise aids in muscle recovery and promotes protein synthesis.

Some athletes and fitness enthusiasts also take BCAAs between meals to maintain amino acid levels throughout the day.

What is the recommended dosage for BCAA supplements?

The recommended dosage of BCAA supplements typically ranges from 5 to 20 grams per day, depending on factors such as body weight, exercise intensity, and individual goals. A common dosage is 5-10 grams taken before, during, or after workouts. It is important to follow the dosage instructions on the product label and consult with a healthcare provider for personalized recommendations.

Are there any side effects of taking BCAA supplements?

BCAA supplements are generally considered safe for most people when taken in recommended doses. However, some potential side effects include:

  • Digestive Issues: Some individuals may experience nausea, bloating, or diarrhea.
  • Interactions with Medications: BCAAs may interact with certain medications, such as those for diabetes or thyroid conditions.
  • Imbalance of Amino Acids: Excessive intake of BCAAs without other essential amino acids can potentially lead to an imbalance.

It’s important to consult with a healthcare provider before starting any new supplement, especially if you have underlying health conditions or are taking medications.

Can BCAA supplements help with weight loss?

BCAA supplements can support weight loss efforts by:

  • Preserving Lean Muscle Mass: During calorie restriction, BCAAs help maintain muscle mass, which is important for a healthy metabolism.
  • Reducing Fatigue: BCAAs can improve workout performance and endurance, allowing for more effective exercise sessions.
  • Supporting Satiety: Some studies suggest that BCAAs may help reduce appetite and promote feelings of fullness.

However, BCAA supplements should be used in conjunction with a balanced diet and regular exercise for optimal weight loss results.

Do BCAA supplements contain calories?

Yes, BCAA supplements do contain calories. On average, BCAAs provide about 4 calories per gram, similar to other proteins. However, the calorie content in BCAA supplements is relatively low, typically ranging from 20 to 40 calories per serving, depending on the dosage.

Are BCAA supplements necessary if I already consume enough protein through my diet?

If you already consume adequate protein through your diet, you may not necessarily need BCAA supplements. Whole protein sources, such as meat, dairy, eggs, and legumes, provide all essential amino acids, including BCAAs. However, BCAA supplements can be beneficial for:

  • Targeted Support: Providing a quick source of amino acids around workouts to enhance performance and recovery.
  • Convenience: Offering an easy way to increase amino acid intake without consuming additional food.
  • Specific Goals: Supporting muscle preservation during calorie restriction or intense training.

Are there any specific populations that should avoid BCAA supplements?

As stated previously, certain populations should exercise caution or avoid BCAA supplements, including:

  • Individuals with Medical Conditions: Those with medical conditions such as kidney or liver disease should consult with a healthcare provider before using BCAA supplements.
  • Pregnant or Breastfeeding Women: There is limited research on the safety of BCAA supplements during pregnancy and breastfeeding, so it’s best to seek medical advice.
  • Children and Adolescents: The safety and efficacy of BCAA supplements for young individuals have not been well-studied.